Nasal and paranasal sinus mucosal melanoma

Authors

DOI:

https://doi.org/10.11606/issn.2176-7262.rmrp.2024.214266

Keywords:

Melanoma, Nasal mucosa, Neoplasm recurrence local, Nose neoplasms

Abstract

Background: Nasosinusal melanoma is a rare and highly aggressive tumor with a high potential for metastasis. It originates from melanocytes in the nasal mucosa and primarily affects the lateral nasal wall, nasal septum, and inferior nasal concha. It is less common in the paranasal sinuses. This type of cancer is known for its high recurrence rate and is most commonly seen in individuals between the ages of 70 and 80, with a slightly higher incidence in females. Case report: This case study discusses a 73-year-old female patient with nasal mucosa melanoma. The tumor was first identified 1.5 years before the initial surgery, and the patient received adjuvant treatments, including immunotherapy. She also underwent a second surgery in an attempt to completely remove the
tumor. However, almost a year after the second surgery, a new mass was discovered in the nasal cavity. Due to the development of distant metastases, further treatment was discontinued, and the patient was referred to palliative care services. Conclusion: Early diagnosis and appropriate treatment are crucial, although they may not always result in a cure due to the aggressive nature of this type of tumor.

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Author Biographies

  • Andressa Vinha Zannuncio, Universidade Federal de São João Del Rei, Divinópolis, (MG), Brasil

    Doutorado em Cirurgia

  • Luciana Menezes Nogueira Martins, Universidade Federal de São João Del Rei, Divinópolis, (MG), Brasil

    Doutorado em Ciências da Saúde da Criança e do Adolescente

  • Jessica Maia Couto Matias, Universidade Federal de São João Del Rei, Divinópolis, (MG), Brasil

    Especialista em otorrinolaringologia 

  • Danielle Ferreira de Souza, Universidade Federal de São João Del Rei, Divinópolis, (MG), Brasil

    Graduanda em Medicina

  • Paula Augusta Silva Santos, Universidade Federal de São João Del Rei, Divinópolis, (MG), Brasil

    Graduanda em Medicina

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Published

2025-04-10

Issue

Vol. 57 No. 4 (2024)

Section

Relato de Caso

License

Copyright (c) 2024 Andressa Vinha Zannuncio, Luciana Menezes Nogueira Martins, Jessica Maia Couto Matias, Danielle Ferreira de Souza, Paula Augusta Silva Santos

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 

 

How to Cite

1.
Zannuncio AV, Martins LMN, Matias JMC, Souza DF de, Santos PAS. Nasal and paranasal sinus mucosal melanoma. Medicina (Ribeirão Preto) [Internet]. 2025 Apr. 10 [cited 2025 Apr. 19];57(4):e-214266. Available from: https://journals.usp.br/rmrp/article/view/214266