Second-Generation central venous catheter in the prevention of bloodstream infection: a systematic review

Authors

  • Janislei Gislei Dorociaki Stocco Universidade Federal do Paraná; Hospital de Clínicas
  • Hellen Hoers Universidade Federal do Paraná; Departamento de Enfermagem
  • Franciele Soares Pott Universidade Federal do Paraná
  • Karla Crozeta Universidade Federal do Paraná; Departamento de Enfermagem
  • Dulce Aparecida Barbosa Universidade Federal do Paraná; Departamento de Enfermagem
  • Marineli Joaquim Meier Universidade Federal do Paraná; Departamento de Enfermagem

DOI:

https://doi.org/10.1590/1518-8345.0756.2722

Abstract

Objective: to evaluate the effectiveness and safety in the use of second-generation central venous catheters impregnated in clorhexidine and silver sulfadiazine when compared with other catheters, being them impregnated or not, in order to prevent the bloodstream infection prevention. Method: systematic review with meta-analysis. Databases searched: MEDLINE, EMBASE, CINAHL, LILACS/SciELO, Cochrane CENTRAL; search in Congress Proceedings and records from Clinical Trials. Results: 1.235 studies were identified, 97 were pre-selected and 4 were included. In catheter-related bloodstream infection, there was no statistical significance between second-generation impregnated catheter compared with the non-impregnated ones, absolute relative risk 1,5% confidence interval 95% (3%-1%), relative risk 0,68 (confidence interval 95%, 0,40-1,15) and number needed to treat 66. In the sensitivity analysis, there was less bloodstream infection in impregnated catheters (relative risk 0,50, confidence interval 95%, 0,26-0,96). Lower colonization, absolute relative risk 9,6% (confidence interval 95%, 10% to 4%), relative risk 0,51 (confidence interval 95% from 0,38-0,85) and number needed to treat 5. Conclusion: the use of second-generation catheters was effective in reducing the catheter colonization and infection when a sensitivity analysis is performed. Future clinical trials are suggested to evaluate sepsis rates, mortality and adverse effects.

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Published

2016-01-01

Issue

Vol. 24 (2016)

Section

Original Articles

License

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Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Second-Generation central venous catheter in the prevention of bloodstream infection: a systematic review . (2016). Revista Latino-Americana De Enfermagem, 24, e2722-. https://doi.org/10.1590/1518-8345.0756.2722