Evaluation of antiretroviral treatment of people living with HIV/sida participating inan adherence group

Abstract

Study design: This is an observational, descriptive, and cross-sectional study. Objective: Evaluating the adherence behavior to the antiretroviral treatment of people living with HIV/Aids who participate in an Adherence Group. Methods: The questionnaire was answered by 15 patients older than 18 years of age, regardless of sex, with a confirmed diagnosis of AIDS participating in an Adherence Group at an antiretroviral dispensing service, who, after receiving information related to the study, agreed to participate voluntarily, by singing the Written Informed Consent Form. Results: The majority of the participants were male, over 40 years old (73.3%) and 26.6% were economically active. Regarding sexuality, 80% of the interviewees stated that they were heterosexual. As for schooling, 60% had not finished high school. The time of diagnosis of the disease predominant was between 10 and 16 years, and 46.6% reported having other health problems, like toxoplasmosis, herpes, tuberculosis, and leishmaniasis. The analysis of the adherence questionnaire showed that 33.3% had good adherence to antiretroviral treatment. Among the drug-drug interactions identified, 44.4% occurred among antirretrovirals. Conclusion: Based on this study, it was possible to conclude that 66,66% at some point there was a discontinuation of treatment, revealing a difficulty in maintaining antiretroviral use in individuals living with HIV/aids. In the scenario of antiretroviral pharmacoepidemiology, the potential drug interactions identified in this study were events that affect the therapeutic response leading to toxicity.