Aspectos evolutivos do splicing alternativo
DOI:
https://doi.org/10.11606/issn.1984-5154.v4p44-49Palavras-chave:
Splicing alternativo, exons, EST, diversidade.Resumo
Os eucariotos apresentam mecanismos muito refinados para o controle de sua expressão gênica, dentre eles, o splicing alternativo. Este mecanismo, abundante entre estes organismos, possibilita a geração de diferentes proteínas a partir de um único gene. Esta revisão pretende mostrar como as características do splicing alternativo podem torná-lo uma ferramenta interessante em estudos com enfoque evolutivo, em questões envolvendo tanto o surgimento do mecanismo quanto sua atuação na diversificação dos seres vivos.
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