Long-term bromopride treatment induces morphological changes in female rats

Authors

  • Luciano Freitas Felicio Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Idercio Luiz Sinhorini Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • João Palermo Neto Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP
  • Antonia Gladys Nasello Faculdade de Ciências Médicas da Santa Casa, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.2318-3659.v25i1p117-121

Keywords:

Bromopride, Oestrous cycle (diestrous), Prolactin

Abstract

There were morphoIogicaIy examined the ovaries, uterus, fallopian tubes and mammary glands of adult female rats, that were long-term treated with bromopride. Large corpus luteum, uterus in a secretory stage and hipertrophiated mammary gland were observed in treated animals. These marked morphological changes were correlated to the neuroendocrinal effects of the drug, considering what it is able to block tuberoinfundibuIar dopamine (DA) receptors leading to an increase in prolactin levels.


Downloads

Download data is not yet available.

Downloads

Published

1988-03-15

Issue

Vol. 25 No. 1 (1988)

Section

ANIMAL PATHOLOGY

How to Cite

Long-term bromopride treatment induces morphological changes in female rats. (1988). Revista Da Faculdade De Medicina Veterinária E Zootecnia Da Universidade De São Paulo, 25(1), 117-121. https://doi.org/10.11606/issn.2318-3659.v25i1p117-121