Antirabies vaccines Flury HEP. II. Comparative study between the mice viability and the guinea pig potency tests

Authors

  • Moacir Rossi Nilsson Instituto Biológico de São Paulo, São Paulo, SP
  • José de Angelis Côrtes Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Veterinária Preventiva e Saúde Animal, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.2318-3659.v15i2p215-224

Keywords:

Rabies, Vaccine Flury-HEP, Guinea pigs potency test, Mice viability test

Abstract

A comparative study between the mice viability test and the guinea pig potency test for the efficiency evaluation of the Flury HEP vaccines revealed a strong positive association between the mice titer and the protection percent of the vaccinated guinea pigs. Although the mice viability test is not able to demonstrate the vaccine immune response, titers of 103,5 or higher constitute a good indication that the vaccine will be approved by the guinea pig potency test.

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Published

1978-09-15

Issue

Vol. 15 No. 2 (1978)

Section

ORIGINAL ARTICLES

How to Cite

Antirabies vaccines Flury HEP. II. Comparative study between the mice viability and the guinea pig potency tests. (1978). Revista Da Faculdade De Medicina Veterinária E Zootecnia Da Universidade De São Paulo, 15(2), 215-224. https://doi.org/10.11606/issn.2318-3659.v15i2p215-224