Regulação gênica dos receptores dos hormônios tireoideanos durante a metamorfose de anfíbios anuros.
DOI:
https://doi.org/10.11606/issn.1984-5154.v4p16-21Palavras-chave:
Glândula Tiróide, Maquinaria de transcrição, Metamorfose, Receptores de hormônios tiroidianos.Resumo
Anfíbios anuros apresentam adaptações morfológicas e fisiológicas para sua vida terrestre. A glândula tiróide é a principal responsável pela metamorfose e esse processo é coordenado pelo eixo hipotálamo-hipófise-tireóide. A cronometragem da metamorfose é então uma função combinada de síntese de hormônios e enzimas e todo esse processo é regulado por expressão gênica de cada componente desse eixo, desde os próprios hormônios envolvidos bem como seus receptores. Neste trabalho foi abordado como ocorre a regulação gênica dos receptores dos hormônios tiroidianos e a importância desse processo para o sucesso evolutivo do grupo.
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