An alternative synthesis of 1,2,3,4-tetrahydro-9H-pyrido-[3,4-b]-indole

Authors

  • Arildo José Braz de Oliveira Universidade Estadual de Maringá; Centro de Ciências da Saúde; Departamento de Farmácia e Farmacologia
  • Luzia Koike Universidade Estadual de Campinas; Instituto de Química

DOI:

https://doi.org/10.1590/S1516-93322003000300005

Keywords:

Indole derivatives, Tranquillizing properties, 3-Indoleacetaldehyde, Pictet-Spengler reaction, Oxidation

Abstract

The 1,2,3,4-tetrahydro-9H-pyrido-[3,4-b]-indole, a compound with tranquillizing properties, was prepared in 16% overall yield from the 3-indole-acetaldehyde and tryptamine by applying the classical Pictet-Spengler condensation. Physical and spectroscopic data for such compound are presented.

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Published

2003-09-01

Issue

Vol. 39 No. 3 (2003)

Section

Original Papers

How to Cite

An alternative synthesis of 1,2,3,4-tetrahydro-9H-pyrido-[3,4-b]-indole. (2003). Revista Brasileira De Ciências Farmacêuticas, 39(3), 259-264. https://doi.org/10.1590/S1516-93322003000300005