Antimicrobial activity in pit and fissure sealants: a systematic review
DOI:
https://doi.org/10.11606/issn.2357-8041.clrd.2022.192671Keywords:
Pit and fissure sealants, Antimicrobial activity, Systematic review, Dental materials, Prevention methodAbstract
Objective: This study aimed to systematically review the literature about sealants modified with materials to promote antimicrobial activity and answer the question “What is the effect of incorporating materials that promote antimicrobial activity to pit and fissure sealants?” Materials and methods: Data were collected from questions about the material incorporated, its concentration, purpose of incorporation, analyses, and conclusions obtained. The Cochrane Library, LILLACS, ScienceDirect, and PubMed databases were searched with the terms “SEALANT”, “ANTIMICROBIAL”, and “ANTIBACTERIAL”. The selection of studies was performed in two stages. Inclusion criteria were applied via the evaluation of titles and abstracts, and exclusion criteria, via the complete reading of the studies. The adapted Joanna Briggs Institute (JBI) tool was used to analyze bias risk. Results: Due to the heterogeneity of the data found, it was impossible to perform a meta-analysis. We obtained 1389 references, including 11 of them in this review. Analysis of the studies found that modified sealants may show antimicrobial activity and alter their other properties. After applying the JBI tool, all studies showed low bias risk. Conclusion: Modified pit and fissure sealants show antimicrobial activity and altered physicochemical and mechanical properties.
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Hesaraki S, Karimi M, Nezafati N. The synergistic effects of SrF2 nanoparticles, YSZ nanoparticles, and poly-ε-L-lysin on physicomechanical, ion release, and antibacterial-cellular behavior of the flowable dental composites. Mater Sci Eng C. 2020;109:110592. Doi: https://doi.org/10.1016/j.msec.2019.110592.
Moreira KMS, Kantovitz KR, Aguiar JPD, Borges AFS, Pascon FM, Puppin-Rontani RM. Impact of the intermediary layer on sealant retention: a randomized 24-month clinical trial. Clin Oral Investig. 2017;21(5):1435-43. Doi: https://doi.org/10.1007/s00784-016-1890-4.
Kantovitz KR, Pascon FM, Nociti FH Jr, Tabchoury CPM, Puppin-Rontani RM. Inhibition of enamel mineral loss by fissure sealant: An in situ study. J Dent. 2013;41(1):42-50. Doi: http://doi.org/10.1016/j.jdent.2012.09.015
Ibrahim MS, Ibrahim AS, Balhaddad AA, Weir MD, Lin NJ, Tay FR, et al. A novel dental sealant containing dimethylaminohexadecyl methacrylate suppresses the cariogenic pathogenicity of Streptococcus mutans biofilms. Int J Mol Sci. 2019;20(14):3491. Doi: https://doi.org/10.3390/ijms20143491.
Yu F, Yu H, Lin P, Dong Y, Zhang L, Sun X, et al. Effect of an antibacterial monomer on the antibacterial activity of a pit-and-fissure sealant. PLoS One. 2016;11(9):e0162281. Doi: https://doi.org/10.1371/journal.pone.0162281.
Papageorgiou SN, Dimitraki D, Kotsanos N, Bekes K, van Waes H. Performance of pit and fissure sealants according to tooth characteristics: A systematic review and meta-analysis. J Dent. 2017;6:8-17. Doi: https://doi.org/10.1016/j.jdent.2017.08.004.
Borges BCD, Souza-Júnior EJ, Catelan A, Lovadino JR, Santos PH, Paulillo LAMS, et al. Influence of extended light exposure time on the degree of conversion and plasticization of materials used as pit and fissure sealants. J Investig Clin Dent. 2010;1(2):151-5. Doi: https://doi.org/10.1111/j.2041-1626.2010.00015.x.
Kloukos D, Pandis N, Eliades T. In vivo bisphenol-A release from dental pit and fissure sealants: A systematic review. J Dent. 2013;41(8):659-67. Doi: http://doi.org/10.1016/j.jdent.2013.04.012
Paris S, Lausch J, Selje T, Dörfer CE, Meyer-Lueckel H. Comparison of sealant and infiltrant penetration into pit and fissure caries lesions in vitro. J Dent. 2014;42(4):432-8. Doi: https://doi.org/10.1016/j.jdent.2014.01.006.
Borges BCD, Bezerra GVG, Mesquita JA, Pereira MR, Aguiar FHB, Santos AJS, et al. Effect of irradiation times on the polymerization depth of contemporary fissure sealants with different opacities. Braz Oral Res. 2011;25(2):135-42. Doi: https://doi.org/10.1590/S1806-83242011000200007.
Hamilton MF, Otte AD, Gregory RL, Pinal R, Ferreira-Zandoná A, Bottino MC. Physicomechanical and antibacterial properties of experimental resin-based dental sealants modified with nylon-6 and chitosan nanofibers. J Biomed Mater Res B Appl Biomater. 2015;103(8):1560-8. Doi: https://doi.org/10.1002/jbm.b.33342.
Fiorati-Aguiar SM, Lucisano MP, Silva LAB, Silva RAB, Spadaro ACC, Borsatto MC, et al. Mechanical, chemical and antimicrobial properties of a bisphenol A-free pit-and-fissure sealant. Am J Dent. 2018;31(6):279-84.
Shanmugaavel AK, Asokan S, John JB, Priya PG, Devi JG. Effect of one percent chlorhexidine addition on the antibacterial activity and mechanical properties of sealants: An in vitro study. Int J Clin Pediatr Dent. 2015;8(3):196-201. Doi: https://doi.org/10.5005/jp-journals-10005-1312.
Garcia IM, Rodrigues SB, Souza Balbinot G, Visioli F, Leitune VCB, Collares FM. Quaternary ammonium compound as antimicrobial agent in resin-based sealants. Clin Oral Investig. 2020;24(2):777-84. Doi: https://doi.org/10.1007/s00784-019-02971-4.
Cocco AR, Cuevas-Suárez CE, Liu Y, Lund RG, Piva E, Hwang G. Anti-biofilm activity of a novel pit and fissure self-adhesive sealant modified with metallic monomers. Biofouling. 2020;36(3):245-55. Doi: https://doi.org/10.1080/08927014.2020.1748603.
Shinonaga Y, Arita K, Nishimura T, Chiu SY, Chiu HH, Abe Y, et al. Effects of porous-hydroxyapatite incorporated into glass-ionomer sealants. Dent Mater J. 2015;34(2):196-202. Doi: https://doi.org/10.4012/dmj.2014-195.
Rajabnia R, Ghasempour M, Gharekhani S, Gholamhoseinnia S, Soroorhomayoon S. Anti-Streptococcus mutans property of a chitosan: Containing resin sealant. J Int Soc Prev Community Dent. 2016;6(1):49-53. Doi: https://doi.org/10.4103/2231-0762.175405.
Garcia IM, Rodrigues SB, Leitune VCB, Collares FM. Antibacterial, chemical and physical properties of sealants with polyhexamethylene guanidine hydrochloride. Braz Oral Res. 2019;33:1-9. Doi: https://doi.org/10.1590/1807-3107bor-2019.vol33.0019.
Monteiro JC, Stürmer M, Garcia IM, Melo MA, Sauro S, Leitune VCB, et al. Dental sealant empowered by 1,3,5-Tri acryloyl hexahydro-1,3,5-triazine and α- tricalcium phosphate for anti-caries application. Polymers (Basel). 2020;12(4):895. Doi: https://doi.org/10.3390/polym12040895.
Tufanaru C, Munn Z, Aromataris E, Campbell J, Hopp L. Systematic reviews of effectiveness. In: Aromataris E, Munn Z, editors. JBI manual for evidence synthesis [Internet]. The Joanna Briggs Institute; 2020 [cited 2022 Feb 1]. Available from: https://synthesismanual.jbi.global/.
Mahapoka E, Arirachakaran P, Watthanaphanit A, Rujiravanit R, Poolthong S. Chitosan whiskers from shrimp shells incorporated into dimethacrylatebased dental resin sealant. Dent Mater J. 2012;31(2):273-9. Doi: https://doi.org/10.4012/dmj.2011-071.
Hosseinnejad M, Jafari SM. Evaluation of different factors affecting antimicrobial properties of chitosan. Int J Biol Macromol. 2016;85:467-75. Doi: http://doi.org/10.1016/j.ijbiomac.2016.01.022.
Nikolaidis A, Vouzara T, Koulaouzidou E. Pit and fissure nanocomposite sealants reinforced with organically modified montmorillonite: A study of their mechanical properties, surface roughness and color stability. Dent Mater J. 2020;39(5):773-83. Doi: https://doi.org/10.4012/dmj.2019-214.
Hasan AMHR, Sidhu SK, Nicholson JW. Fluoride release and uptake in enhanced bioactivity glass ionomer cement (“glass carbomerTM”) compared with conventional and resin-modified glass ionomer cements. J Appl Oral Sci. 2019;27:1-6.
Okuyama K, Matsuda Y, Yamamoto H, Tamaki Y, Saito T, Hayashi M, et al. Fluorine distribution from fluoride-releasing luting materials into human dentin. Nucl Instrum Methods Phys Res B. 2019;456:16-20. Doi: https://doi.org/10.1016/j.nimb.2019.06.047
Yasuhiro M, Katsushi O, Hiroko Y, Hisanori K, Masashi K, Takahiro S, et al. Fluorine uptake into the human enamel surface from fluoride-containing sealing materials during cariogenic pH cycling. Nucl Instrum Methods Phys Res B. 2015;348:156–9. Doi: http://doi.org/10.1016/j.nimb.2015.01.062.
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