Vol. 50 No. 2 (2014)

Published: 2014-04-01

Articles

Evaluation of cytotoxicity and mutagenicity of the benzodiazepine flunitrazepam in vitro and in vivo

Igor Vivian de Almeida, Giovana Domingues, Lilian Capelari Soares, Elisângela Düsman, Veronica Elisa Pimenta Vicentini

251-256
- PDF
Sucrose hydrolysis by invertase using a membrane reactor: effect of membrane cut-off on enzyme performance

Francesco Di Addezio, Ester Junko Yoriyaz, Maria Cantarella, Michele Vitolo

257-259
- PDF
A novel validated UPLC method for quantitation of lopinavir and ritonavir in bulk drug and pharmaceutical formulation with its impurities

Gnana Deepika Killi, Rama Krishna Maddinapudi, Sathis Kumar Dinakaran, Avasarala Harani

301-308
- PDF
Hypotensive effect and endothelium-dependent vascular action of leaves of Alpinia purpurata (Vieill) K. Schum

Alessandra Tesch da Silva, Ewelyne Miranda de Lima, Isabela Faco Caliman, Leonardo Luiz Souza Porto, Andrews Marques do Nascimento, Iêda Carneiro Kalil, Dominik Lenz, Nazaré Souza Bissoli, Denise Coutinho Endringer, Tadeu Uggere de Andrade

309-320
- PDF
Isolation and characterization of lactic acid bacteria and yeasts from the Brazilian grape sourdough

Krischina Singer Aplevicz, Jaciara Zarpellon Mazo, Eunice Cassanego Ilha, Andréia Zilio Dinon, Ernani Sebastião Sant´Anna

321-327
- PDF
Development of dissolution test method for a telmisartan/amlodipine besylate combination using synchronous derivative spectrofluorimetry

Panikumar Durga Anumolu, Sirisha Neeli, Haripriya Anuganti, Sathesh Babu Puvvadi Ranganatham, Subrahmanyam Chavali Venkata Satya

329-336
- PDF
Validation of high-performance liquid chromatographic method for analysis of fluconazole in microemulsions and liquid crystals

Hilris Rocha e Silva, Fernanda Kolenyak dos Santos, Gabriela Marielli da Luz, Marlus Chorilli, Maria Palmira Daflon Gremião

381-389
- PDF
Development and physical evaluation of Maytenus ilicifolia effervescent granules using factorial design

Marcilio Sérgio Soares da Cunha-Filho, Pricila Castilho Gustmann, Felipe Sanches Garcia, Eliana Martins Lima, Lívia Cristina Lira de Sá-Barreto

243-250
- PDF
Genetic heterogeneity of Escherichia coli isolated from pasteurized milk in State of Paraná, Brazil

Karine Oltramari, Rosilene Fressati Cardoso, Eliana Valéria Patussi, Adolfo Carlos Barreto Santos, Jane Martha Graton Mikcha

337-343
- PDF
Characterization and stability studies of emulsion systems containing pumice

Marilene Estanqueiro, Jaime Conceição, Maria Helena Amaral, Delfim Santos, João Baptista Silva, José Manuel Sousa Lobo

361-369
- PDF
The influence of pH, polyethylene glycol and polyacrylic acid on the stability of stem bromelain

Letícia Celia de Lencastre Novaes, Angela Faustino Jozala, Priscila Gava Mazzola, Adalberto Pessoa Júnior

371-380
- PDF
Development and validation of a dissolution method using HPLC for diclofenac potassium in oral suspension

Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Luciane Varini Laporta, Clarice Madalena Bueno Rolim

423-429
- PDF
Influence of papain in biofilm formed by methicillin-resistant Staphylococcus epidermidis and methicillin-resistant Staphylococcus haemolyticus isolates

Hanna Lara da Cruz Dinéas de Oliveira, Maria Emília Castro Kling Fleming, Patrícia Vollu Silva, Geraldo Renato de Paula, Débora Omena Futuro, Guillermo Coca Velarde, Luciana Maria Ramires Esper, Lenise Arneiro Teixeira

261-267
- PDF
Cytotoxicity and DNA damage in the neutrophils of patients with sickle cell anaemia treated with hydroxyurea

Alano Martins Pedrosa, Maritza Cavalcante Barbosa, Thayna Nogueira dos Santos, Luzia Kalyne Almeida Moreira Leal, Amanda de Araújo Lopes, Darcielle Bruna Dias Elias, Greyce Luri Sasahara, Bruno Coêlho Cavalcanti, Romélia Pinheiro Gonçalves

401-410
- PDF
Assessment of analytical techniques for characterization of crystalline clopidogrel forms in patent applications

Luiz Marcelo Lira, Alexandre Lopes Lourenço, Guilherme Ferreira Neves, Valéria Pereira de Sousa, Carlos Rangel Rodrigues, Lúcio Mendes Cabral

229-242
- PDF
Safety assessment of essential medicines for elderly people: a bibliographic survey

Fabiana Rossi Varallo, Fernanda Mariana de Oliveira, Patrícia de Carvalho Mastroianni

269-284
- PDF
Obligations, precautions and pending issues in regulatory development for radiopharmaceuticals in Brazil

Maryelle Moreira Lima Gamboa, Heveline Rayane Moura Roesch, Vanessa Pinheiro Amaral Lemos, Bruna Oliveira Rocha, Ralph Santos-Oliveira

285-290
- PDF
Preparation and scale up of extended-release tablets of bromopride

Guilherme Neves Ferreira, Marcos Giovani Rodrigues Silva, Aline Guerra Manssour Fraga, Luiz Cláudio Rodrigues Pereira da Silva, Luiz Marcelo Lira, Carlos Rangel Rodrigues, Helena Carla Castro, Valéria Pereira de Sousa, Lucio Mendes Cabral

291-300
- PDF
Chronic Hepatitis C treatment for genotype 2 or 3 in Brazil: cost effectiveness analysis of peginterferon plus ribavirin as first choice treatment

Carine Raquel Blatt, Bernd Storb, Nikolai Mühlberger, Mareni Rocha Farias, Uwe Siebert

345-352
- PDF
Passiflora incarnata treatment during gestation and lactation: toxicological and antioxidant evaluation in wistar dams

Karine Maria Boll, Chiara Cristina Bortolasci, Tiago Zaminelli, Luiz Fernando Veríssimo, André Demambre Bacchi, Luciana Higachi, Décio Sabbatini Barbosa, Estefânia Gastaldello Moreira

353-359
- PDF
Studies on the formation and forming mechanism of the related substance E in potassium clavulanate production by HPLC-MS/MS

Chuanqing Zhong, Guangxiang Cao, Xiaoqing Jin, Fengshan Wang

391-399
- PDF
Pharmacovigilance in oncology: pattern of spontaneous notifications, incidence of adverse drug reactions and under-reporting

Marília Berlofa Visacri, Cinthia Madeira de Souza, Rafaela Pimentel, Cristina Rosa Barbosa, Catarina Miyako Shibata Sato, Silvia Granja, Mécia de Marialva, Carmen Silvia Passos Lima, Priscila Gava Mazzola, Patrícia Moriel

411-422
- PDF
Formulation of gastroretentive floating drug delivery system using hydrophilic polymers and its in vitro characterization

Venkata Srikanth Meka, Senthil Rajan Dharmanlingam, Venkata Ramana Murthy Kolapalli

431-439
- PDF