Profile of drugs used by university students for self-medication in times of the COVID-19 pandemic
A scoping review
DOI:
https://doi.org/10.1590/Keywords:
Review, Students, Self-Medication, COVID-19, Drug UtilizationAbstract
A significant increase in self-medication was observed during the SARS-CoV-2 pandemic, especially among university students due to their higher level of knowledge and awareness, making them more prone to self-medication. Therefore, in this scoping review we aimed to understand the profile of medications used for self-medication among university students during the pandemic, both for COVID-19 prevention and other reasons. We followed the PRISMA-ScR guidelines in conducting the review. The PICo guiding question was, “What is the profile of medications used for self-medication during the COVID-19 pandemic among university students?” Searches were conducted in the Scielo, PubMed, Embase, EBSCOhost, Web of Science, Scopus, BVS, Google Scholar, and CAPES databases based on MESH and DeCS descriptors. A total of 35 studies were selected, with eight (22.8%) reporting self-medication for COVID-19 prevention/treatment ranging from 14-83%, four (11.4%) reporting self-medication for specific symptoms ranging from 11-95%, 19 (54.4%) reporting several reasons for students self-medicating with a range of 50-100%, and four (11.4%) studies not specifying the reason for medication use in self-medication varying from 3-93%. The included studies revealed that the irrational use of medications is a common practice among university students, with varied prevalence of self-medication observed in this population during the COVID-19 pandemic.
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Alahendra AMAAU, Pereira OTS, Guruge ML, Anthony DK, Dasanayaka C, Wijekoon WMPDS. Perceived Self- medication Practices and Associated Factors among Undergraduates in a Non-State University. 2021. SLIIT J Humanit Sci. 2021;2(1):29-47.
Albuquerque AV, Tavares DPS, Silva LB, Marques RAC, Almeida ACG. Estratégias associadas à prevenção da resistência de antimicrobianos no âmbito hospitalar: Revisão sistemática. Res, Soc Development. 2022;11(7): 23811729990.
Alduraibi RK, Altowayan WM. A cross-sectional survey: knowledge, attitudes, and practices of self-medication in medical and pharmacy students. BMC Health Serv Res. 2022;22(1):352.
Alhaj HHM, Al-lahawi AMB, Al-abeed M, Omer MEA, F. Abubakar Y. Misuse of antibiotic among university and higher education students in Sudan a cross-sectional. 2021. PREPRINT (Version 1) available at Research Square. 2021.
Al-Qahtani AM, Shaikh IA, Shaikh MAK, Mannasaheb BA, Al-Qahtani FS. Prevalence, perception, and practice, and attitudes towards self-medication among undergraduate medical students of Najran University, Saudi Arabia: A cross-sectional study. Risk Manag Healthc Policy. 2022;16(15):257-276.
Alshammari F, Alobaida A, Alshammari A, Alharbi A, Alrashidi A, Almansour A, et al. University Students’ Self-Medication Practices and Pharmacists’ Role: A Cross- Sectional Survey in Hail, Saudi Arabia. Front Public Health. 2021;17(9):779107.
Alves MCGS. Avaliação da prática de automedicação por alunos do curso de Saúde Coletiva da Universidade Federal do Sul e Sudeste do Pará durante a pandemia de COVID-19. [Trabalho de Conclusão de Curso].Marabá: Universidade Federal do Sul e Sudeste do Pará, Faculdade de Saúde Coletiva,2022.
Andrade EA, Moreno VG, Ortiz M. Perfil de uso de medicamentos e automedicação, em uma população universitária, frente à pandemia da Covid-19 / Profile of use of medicines and self-medication, in a university population, in front of Covid-19 pandemic. Braz J Dev. 2021;7(7):73772-73784.
Armillo CM, Corsiga AJS, Enriquez RMG, Libang JD, Lucban JMP, Roxas MAM, et al. Level of self- medication awareness to internet usage among selected, non-medical students in Centro Escolar university-Manila during COVID-19 pandemic. GSC Biol Pharm Sci. 2022;20(02):152-163.
Behzadifar M, Behzadifar M, Aryankhesal A, Ravaghi H, Baradaran HR, Sajadi HS, et al. Prevalence of self-medication in university students: systematic review and meta-analysis. East Mediterr Health J. 2020;26(7):846- 857.
Bello IB, Akinnawo EO, Akpunne BC, Egbunu. Knowledge of COVID-19 and preventive measures on self-medication practices among Nigerian undergraduates. Cogent Arts Humanities. 2022;9:2049480.
Brasil. Ministério da Saúde. Manejo terapêutico da Síndrome Gripal na APS. [Internet] Brasília (DF): Ministério da Saúde, 2020a. [cited 2022 dec 13]. Available from: Available from: https://saude.rs.gov.br/upload/arquivos/202004/14140606-4-ms-protocolomanejo-aps-ver07abril.pdf
» https://saude.rs.gov.br/upload/arquivos/202004/14140606-4-ms-protocolomanejo-aps-ver07abril.pdf
Brasil. Ministério da Saúde. Uso racional de medicamentos. [Internet] Brasília (DF): Ministério da Saúde , 2013. [cited 2022 dec 15]. Available from: Available from: https://www.gov.br/saude/pt-br/composicao/sctie/daf/uso-racional-de-medicamentos
» https://www.gov.br/saude/pt-br/composicao/sctie/daf/uso-racional-de-medicamentos
Brasil. Ministério da Saúde.Cuidado com as Fake News. [Internet] Brasília (DF): Ministério da Saúde , 2020b. [cited 2022 dec 13]. Available from: Available from: https://coronavirus.rs.gov.br/cuidado-com-as-fake-news
» https://coronavirus.rs.gov.br/cuidado-com-as-fake-news
JCM, Lima WG, Cardoso BG, Simião DC, Amorim JM, Silva CA. Uso irracional de medicamentos e plantas medicinais contra a COVID-19 (SARS-CoV-2): um problema emergente. Brazilian J H Pharm. 2020;2(3):37-53. [cited 2022 dec 13] Available from: Available from: https://revistacientifica.crfmg.emnuvens.com.br/crfmg/article/view/102/66
» https://revistacientifica.crfmg.emnuvens.com.br/crfmg/article/view/102/66
Cândido RCF, Perini E, Pádua CMD, Junqueira DR. Prevalência e fatores associados ao uso de metilfenidato para neuroaprimoramento farmacológico entre estudantes universitários. Einstein (São Paulo). 2019;18:eAO4745.
Cienfuegos B, Alexandre C, Falla C, Claudia A. Factores relacionados con la automedicación en estudiantes de Medicina Humana de la Universidad Señor de Sipán. [Tesi el título profesional de médico cirujano]. Perú: Universidad Señor de Sipán, 2022.
Conselho Federal de Farmácia (CFF). Venda de Medicamentos Psiquiátricos cresce na pandemia. [cited 2022 dec 09]. Available from: Available from: https://cff.org.br/noticia.php?id=6015
» https://cff.org.br/noticia.php?id=6015
Cvitković M. Use of antidepressants in the student population. [Tese] .Zagreb:Faculty of Pharmacy and Biochemistry;University of Zagreb, 2021.
Dantas FSE, Coutinho VEA, de Abreu Carolino R, Sarmento TDAB, da Cunha CVL, da Silva, CP, Ferreira ML. Automedicação no contexto de COVID-19, os perigos da prática e fatores associados. Res, Soc Dev. 2023;12(6):e11912642039-e11912642039.
Escobar LE, Villanueva CAB, Corales RV, Palacios MIP, Reyes MAV. Factores relacionados con la automedicación en estudiantes de ciencias de la salud. Universidad y Sociedad. [cited 2022 dec 09].2022;14(3):460-8. Available from: Available from: https://rus.ucf.edu.cu/index.php/rus/article/view/2886
» https://rus.ucf.edu.cu/index.php/rus/article/view/2886
Elayeh E, Akour A, Haddadin RN. Prevalence and predictors of self-medication drugs to prevent or treat COVID-19: Experience from a Middle Eastern country. International journal of clinical practice. 2021;75(11):e14860.
Fallah G, Moudi S, Hamidia A, Bijani A. Stimulant use in medical students and residents requires more careful attention. Caspian J Intern Med. 2018;9(1):87-91.
Faria LB, Costa ACC, Costa CCF, Silva FC, Ribeiro GR. Automedicação entre os estudantes de medicina de uma instituição de ensino superior de Anápolis- GO. [Trabalho de curso]. Anápolis: Universitário Centro de Anápolis, Unievangélica, 2020.
Fetensa G, Tolossa T, Etafa W, Fekadu G. Prevalence and predictors of self-medication among university students in Ethiopia: a systematic review and meta-analysis. J Pharm Policy Pract. 2021;14,107.
Food and Drug Administration (FDA). Atualização sobre o coronavírus (COVID-19): FDA adverte o vendedor que comercializa produtos perigosos de dióxido de cloro que alegam tratar ou prevenir COVID-19. 2020. [cited 2022 dec 09]. Available from: Available from: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-warns-seller-marketing-dangerous-chlorine-dioxide-products-claim
Fundação Oswaldo Cruz (Fiocruz). Ministério da saúde. (Brasil). Antibióticos: resistência de microrganismos é grave ameaça à saúde global. [Internet] Brasília (DF): Ministério da Saúde , 2019. [cited 2022 dec 14]. Available from:Available from:https://portal.fiocruz.br/noticia/antibioticos-resistencia-de-microrganismos-e-grave-ameaca-saude-global
González GM, Guitiérrez MLY, Estrada KR, Santiago OG. Automedicación para la prevención del covid-19 en estudiantes universitarios del noreste de méxico. Interciencia. 2022;47(6):0378-1844.
Grigoryan L, Haaijer-Ruskamp FM, Burgerhof JG, Mechtler R, Deschepper R, Tambic-Andrasevic A, et al. Self-medication with antimicrobial drugs in Europe. Emerg Infect Dis. 2006;12(3):452-9.
Guedes RAC, Álvares ACM. O uso racional de antimicrobianos como prevenção da resistência bacteriana. 2017. [cited 2023 jan 14]. Available from: Available from: http://www.senaaires.com.br/wp-content/uploads/2017/05/o-uso-racional-de-antimicrobianos-como-preven%C3%87%C3%83o-da-resist%C3%8Ancia- bacteriana.pdf
» http://www.senaaires.com.br/wp-content/uploads/2017/05/o-uso-racional-de-antimicrobianos-como-preven%C3%87%C3%83o-da-resist%C3%8Ancia- bacteriana.pdf
Infectious diseases society of America (IDSA). IDSA Guidelines on the Treatment and Management of Patients with COVID-19. 2022. [cited 2022 dec 13]. Available from: Available from: https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#null
» https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#null
Johora F, Abbsy AA, Jeenia FT, Sojib, FA, Sabiha K, Khan MM, et al. Viewpoint Regarding COVID-19 Vaccine and Pursuing Self-medication amidst Medical Students. Int J Pharma Sci Res (IJPSR). 2020;11:0975-9492
Kazemioula G, Golestani S, Alavi SMA, Taheri F, Gheshlagh R, Lotfalizadeh MH. Prevalence of self-medication during the COVID-19 pandemic: A systematic systematic review and meta-analysis. Front. Saúde Pública. 2022;10:1041695.
Lei X, Jiang H, Liu C, Ferrier A, Mugavin J. Self- Medication Practice and Associated Factors among Residents in Wuhan, China. Int J Environ Res Public Health. 2018; 15(1):68.
Lima DS, Guedes JPM. Atribuições do farmacêutico no Uso racional de medicamentos e automedicação. Research, Society and Development. 2021;10(15): 263101522827.
Malik M, Tahir MJ, Jabbar R, Ahmed A, Hussain R. Self- medication during Covid-19 pandemic: challenges and opportunities. Drugs Ther Perspect. 2020; 36(12):565-567.
Mannasaheb BA, Al-Yamani MJ, Alajlan SA, Alqahtani LM, Alsuhimi SE, Almuzaini RI, et al. Knowledge, Attitude, Practices and Viewpoints of Undergraduate University Students towards Self-Medication: An Institution-Based Study in Riyadh. International Journal of Environmental Research and Public Health. 2021 ;18(16):8545.
Marra LP, Oliveira Jr HA, Medeiros FC, Brito GV, Matuoka JY, Parreira PCL, et al. Ivermectina para covid-19. Revisão sistemática rápida. Revisão sistemática rápida. [cited 2022 dec 13]. Available from: Available from: https://oxfordbrazilebm.com/index.php/2020/05/07/ivermectina-para-otratamento-de-pacientes-com-covid-19-revisao-sistematica-rapida2/
Maurício FD. Avaliação da prática de automedicação pelos estudantes da UFCG - Campus Cuité durante a pandemia da Covid - 19. [Trabalho de Conclusão de Curso]. Cuité:Universidade Federal de Campina Grande; 2022.
Melo JR, Duarte EC, Moraes MV, Fleck K, Arrai, PSD. Automedicação e uso indiscriminado de medicamentos durante a pandemia da COVID-19. Cadernos de Saúde Pública, 2021;37(4):00053221.
Mendes GB. Uso racional de medicamentos: o papel fundamental do farmacêutico. Ciênc. Saúde Coletiva 13. 2008;13:569-571.
Miñan-Tapia A, Conde-Escobar A, Calderon-Arce D, Cáceres-Olazo D, Peña-Rios AJ, Donoso-Romero RC. Fatores associados à automedicação com medicamentos relacionados à COVID-19 em estudantes de ciências da saúde de uma cidade peruana [Internet]. Pré-impressões SciELO. 2020 [cited 2022 dec. 09]. Available from: Available from: https://preprints.scielo.org/index.php/scielo/preprint/view/1225
» https://preprints.scielo.org/index.php/scielo/preprint/view/1225
Misli SBM, Yusof AAP, Masri AM, Halimaton T, Kunjukunju A. Knowledge Attitude, and Practice of Undergraduate Nursing Students Regarding Self- Medication. SSRG International Journal of Nursing and Health Science. 2021;7:1-7.
de Moraes LGM, Bernardina LSD, Andriato LC, Dalvi LR, de Sousa Loyola YC. Automedicação em acadêmicos de Medicina. ver Soc Bras Clín Méd. 2018;16(3):167-170.
Mostajo-Radji MA. Pseudoscience in the times of crisis: How and why chlorine dioxide consumption became popular in Latin America during the COVID-19 pandemic. Frontiers in Political Science. 2021;3:25.
Nobre Junior NFN, Andrade LG. Atenção farmacêutica e a promoção do Uso racional de medicamentos . Revista Ibero-Americana de Humanidades, Ciências e Educação. 2022;8(3):1156-1166.
Organização Pan-Americana da Saúde (OPAS). World Health Organization (WHO). La OPS no recomienda tomar productos que contengan dióxido de cloro, clorito de sodio, hipoclorito de sodio o derivados, 16 de julio del 2020. [cited 2022 dec 13]. Available from: Available from: https://iris.paho.org/handle/10665.2/52484
» https://iris.paho.org/handle/10665.2/52484
Okoye OC, Adejumo OA, Opadeyi AO, Madubuko CR, Ntaji M, Okonkwo KC, et al. Self medication practices and its determinants in health care professionals during the coronavirus disease-2019 pandemic: cross-sectional study. Int J Clin Pharm. 2022;44(2):507-516.
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid AK. Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016;5:1-10.
Palikhey A, Shrivastava AK, Shrestha L, Gurung S, Yadav CK, Pandit M, et al. Self-medication Practices among Medical and Non-medical Students of Siddharthanagar, Nepal during COVID-19 Pandemic. Journal of KIST Medical College. 2021;3(6):40-48.
Popp M, Reis S, Schießer S, Hausinger RI, Stegemann M, Metzendorf MI, et al. Ivermectin for preventing and treating COVID-19. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews 2022, Issue 6. Art. No.: CD015017.
Quincho-Lopez A, Benites-Ibarra CA, Hilario-Gomez MM, Quijano-Escate R, Taype-Rondan A (2021) Self- medication practices to prevent or manage COVID-19: A systematic review. PLOS ONE. 2021;16(11):0259317
Remião, F. O paracetamol e a COVID-19. 2020. Rev. Ciência Elem. 2020, 8(2):023.
Roblero AGT, Toledo AGV, Cruz SY, Díaz CMZ, Sarmiento WZ. Prevalencia del consumo de analgésicos en estudiantes de medicina durante las clases virtuales enero - junio 2022. AMU. 2022;1(02):117-28.
Rojas-Miliano C, Caseres DNG, Zárate-Vargas AM, Araujo-Ramos G, Rosales-Guerra, J, Quiñones- Laveriano DM. Características y factores asociados a la automedicación por COVID-19 en estudiantes de una universidad peruana. Revista Cubana de Farmacia. 2022;55(1):712.
Saleem RT, Butt MH, Ahmad A, Amin M, Amir A, Ahsan A et al. Practices and Attitude of Self-medication during COVID-19 Pandemic in University Students with Interventional Role of Pharmacist: a Regional Analysis 2021. Revista Latino-Americana de Farmácia. 2021;40(8):1946-53.
Santos ELG, Pereira LLP, Seabra ADBMH, Fonseca, AA, Freitas TF, Pereira, EJ et al. Comportamento de estudantes universitários da área da saúde com relação à utilização de medicamentos e a prática da automedicação. Research, Society and Development . 2022;11(12):130111234353.
Sapana AR, Rodríguez HA, Salcedo VJL, Hernandez LFE, Ancachi CM, Camaticona WL, Huanco DA. Factores asociados a la práctica de automedicación en estudiantes de Medicina. RMB. 2021;15(2):37-49.
Sarango KAR, Siguenza JIT, Unuzungo MZA, Bermeo FIZ. Factores que influyen en la automedicación durante la pandemia en estudiantes universitarios. Revista Estudiantil CEUS. 2020,2:13-18.
Shrestha JTM, Kushwaha DK, Tiwari S, Bhattarai P. Study of Self-medication among First and Seventh Semester Medical and Dental Undergraduate Students of Tertiary Care Teaching Hospital in Nepal: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2021;59(233):55-60.
Silva J, Vieira P, Gomes AL, Roth T, Azevedo MHP, Marques DR.Sleep difficulties and use of prescription and non-prescription sleep aids in Portuguese higher education students. Sleep Epidemiology. 2021a;1:100012.
Silva Júnior JGS, Tavares CGS, Monte TVS, Nascimento WM, Oliveira JRS, Callou MAM. Automedicação com antibióticos e suas consequências fisiopatológicas: uma revisão. Rev Rios Saúde. 2018;1:1.
Silva VMP, Oliveira HJP, Souza WK, Souza DM, Santana JAR , Canejo SP, et al. Perfil epidemiológico do uso de medicamentos entre estudantes universitários. REAS. 2021b;13(10):9030.
Sljivo A, Smailbegovic FG, Mulać A, Dadic I, Kubat A, Sirucic I. Mental Health and Substance Abuse Among the Bosnia and Herzegovina Student Population During the COVID-19 Outbreak. Mater Sociomed. 2022;34(1):8-13.
Soriano-Moreno DR, Fernandez-Guzman D, Ccami-Bernal F, Rojas-Miliano C, Nieto-Gutierrez W. Factors associated with the consumption of chlorine dioxide to prevent and treat COVID-19 in the Peruvian population: a cross- sectional study. BMC Public Health. 2021;21(1):2109.
Souza KB. Avaliação e fatores associados à prática de automedicação para prevenção ou tratamento de covid-19 na população universitária do sul do brasil. [Dissertação]. Rio Grande: Universidade Federal do Rio Grande; 2022.
Souza MNC, Ricardino IEF, Sampaio K, Silva MR, Lima APG, Fernandes DL, et al. Ocorrência de Automedicação na população Brasileira como estratégia preventiva ao SARS-CoV-2. Research, Society and Development . 2021;10(1):44510111933.
Subedi C. Self-Medication Practices in Pokhara: A Study of Knowledge and Purpose among Non-Medical Students. Prithvi J Res Innov. 2021;3(1):52-60.
Tavares BLC, Gomes LES. Uso indiscriminado de medicamentos e automedicação no Brasil. Centro de Informações de Medicamentos (CIM). Universidade Federal da Paraíba (UFPB). 2020 [cited 2022 dec.15]. Available from: Available from: https://www.ufpb.br/cim/contents/menu/publicacoes/cimforma/uso-indiscriminado-de-medicamentos-e-automedicacao-no-brasil
Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467-473.
Tritany RF, Tritany EF. Uso racional de medicamentos para COVID-19 na Atenção Primária à Saúde. Saúde em Redes. 2020;6(2).
Wegbom AI, Edet CK, Raimi O, Fagbamigbe AF, Kiri VA . Self-medication practices and associated factors in the prevention and/or treatment of COVID-19 virus: a population-based survey in Nigeria. Front Public Health . 2021:(9);606801.
Witteveen, LA. Non-medical use of ADHD prescription drugs among US college students at a public research university in a small rural town. Honors College Theses 672; 2021. [cited 2023 jan.15]. Available from: Available from: https://digitalcommons.georgiasouthern.edu/honors-theses/672/
» https://digitalcommons.georgiasouthern.edu/honors-theses/672/
Wong A. COVID-19 e toxicidade de tratamentos potenciais: Panaceia ou veneno. Emerg Med Australas. 2020;32(4):697-699.
World Health Organization (WHO). Promoting rational use of medicines: core components. World Health Organization. 2002. [cited 2023 jan.15]. Available from: Available from: https://apps.who.int/iris/handle/10665/67438
» https://apps.who.int/iris/handle/10665/67438
World Health Organization (WHO). Therapeutics and COVID-19: living guideline. 2022. [Internet] [cited 2022 dec 13]. Available from: Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-therapeutics-2022.4
» https://www.who.int/publications/i/item/WHO-2019-nCoV-therapeutics-2022.4
Yasmin F, Asghar MS, Naeem U, Najeeb H, Nauman H, Ahsan MN, et al. Self-Medication Practices in Medical Students During the COVID-19 Pandemic: A Cross-Sectional Analysis. Front Public Health . 2022;9(10):803937.
Yousaf MA, Zahid H, Khalid Z, Khan AT-A, Noreen M, Saleem T, et al. Knowledge, attitude and practices of university students of pakistan towards antibiotic use and resistance: Questionnaire based assessment. BioScientific Review. 2021;3(3):63-82.
Zeb S, Mushtaq M, Ahmad M, Saleem W, Rabaan AA, Naqvi BSZ, et al. Self-Medication as an Important Risk Factor for Antibiotic Resistance: A Multi- Institutional Survey among Students. Antibiotics (Basel). 2022;11(7):842.
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