Antioxidant activity of ethyl acetate and methanolic extracts of two marine algae, Nannochloropsis oculata and Gracilaria gracilis - an in vitro assay

Authors

  • Mohammad Ali Ebrahimzadeh Mazandaran University of Medical Sciences; School of Pharmacy; Pharmaceutical Sciences Research Center
  • Masoumeh Khalili Golestan University of Medical Sciences; Neurosciences Research Center
  • Abbas Ali Dehpour Islamic Azad University; Department of Biology

DOI:

https://doi.org/10.1590/s2175-97902018000117280

Keywords:

Marine algae/antioxidant activity, Nannochloropsis Oculata/total phenol/total flavonoid/ Gracilaria Gracilis/total phenol/total flavonoid

Abstract

The aim of this study was to evaluate the antioxidant activity of ethyl acetate and methanolic extracts of two marine algae, Nannochloropsis oculata and Gracilaria gracilis. The extracts were assayed for total phenol and flavonoid content, DPPH free radical scavenging capacity, nitric oxide activity, iron chelation activity, and reducing power activity. Total phenol and flavonoid content were found to be high in both algae. Ethyl acetate extracts of both algae were found to exhibit significant antioxidant activity. Ethyl acetate extract of N. oculata exhibited a good capacity for iron chelation, nitrate oxide, and scavenging DPPH free radicals (72.95±2.30, 73.73±1.76, and 39.03±0.97% inhibition at 400 µg mL-1 respectively).

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Published

2018-06-07

Issue

Vol. 54 No. 1 (2018)

Section

Articles

License

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.

The on-line journal has open and free access.

How to Cite

Antioxidant activity of ethyl acetate and methanolic extracts of two marine algae, Nannochloropsis oculata and Gracilaria gracilis - an in vitro assay. (2018). Brazilian Journal of Pharmaceutical Sciences, 54(1), e17280. https://doi.org/10.1590/s2175-97902018000117280