Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil

Authors

  • Carolina Sette Barbosa Damasceno Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Fitoquímica
  • Letícia Freire de Oliveira Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Farmacotécnica
  • Ellis Marina Szabo Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Fitoquímica
  • Ângela Maria Souza Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Farmacotécnica
  • Josiane Fatima Gaspari Dias Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Farmacotécnica
  • Marilis Dalarmi Miguel Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Farmacotécnica
  • Obdúlio Gomes Miguel Universidade Federal do Paraná; Departamento de Farmácia; Laboratório de Fitoquímica

DOI:

https://doi.org/10.1590/s2175-97902017000417298

Keywords:

Ocotea bicolor/Oil essential/chemical composition, Lauraceae, Antioxidant activity, Biological activity

Abstract

The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), β-sesquiphellandrene (6.67%), β-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 μg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (μg/mL), being toxic to the organisms in this study.

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Published

2017-01-01

Issue

Vol. 53 No. 4 (2017)

Section

Articles

License

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.

The on-line journal has open and free access.

How to Cite

Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil. (2017). Brazilian Journal of Pharmaceutical Sciences, 53(4), e17298. https://doi.org/10.1590/s2175-97902017000417298