Implementation of a penicillin allergy skin test

Authors

  • Aparecida Tiemi Nagao-Dias Federal University of Ceará; Faculty of Pharmacy; Department Clinical Analysis and Toxicology
  • Ana Carla Pereira Federal University of Ceará; Faculty of Pharmacy; Department Clinical Analysis and Toxicology
  • Michelly Freitas e Silva Federal University of Ceará; Faculty of Pharmacy; Department Clinical Analysis and Toxicology
  • Eugenie Desiree Rabelo Néri Walter Cantídio University Hospital
  • José Wilson Accioly Walter Cantídio University Hospital; Department of Dermatology
  • Janete Elisa Soares Lima Federal University of Ceará; Faculty of Pharmacy; Department Pharmacy

DOI:

https://doi.org/10.1590/S1984-82502009000300023

Keywords:

Penicilin^i1^salle, Penicilin^i1^scutaneous t, Skin test^i1^spenicilin alle, Betalactamic^i1^shipersensitiv

Abstract

The penicillin allergy skin testing is the only accurate and reliable test for penicillin hypersensitivity mediated by IgE. It is useful for identifying patients with doubtful history of allergy. Positive test for major and minor determinants presents a positive predictive value of 50% and negative predictive value of 99%. In Brazil, the Ministry of Health suggests a protocol for in house made reagents, since they are not commercially available. As the referred protocol does not mention some important details about the test procedures, we propose in the present work to implement them, critically evaluating each step in order to allow the protocol establishment at any health service, with quality and safety.

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Published

2009-09-01

Issue

Vol. 45 No. 3 (2009)

Section

Original Papers

License

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.

The on-line journal has open and free access.

How to Cite

Implementation of a penicillin allergy skin test . (2009). Brazilian Journal of Pharmaceutical Sciences, 45(3), 567-572. https://doi.org/10.1590/S1984-82502009000300023