Factors associated with adherence to immunomodulator treatment in people with multiple sclerosis

Authors

  • Nair Assunta Antônia Corso Câmara Fortaleza General Hospital
  • Ana Paula Soares Gondim Federal University of Ceará; Faculty of Pharmacy, Dentistry and Nursing; Department of Pharmacy

DOI:

https://doi.org/10.1590/s2175-97902017000116132

Keywords:

Multiple sclerosis/medication adherence, Multiple sclerosis/treatment, Immunologic factors, Risk factors.

Abstract

To determine the association between factors and adherence to immunomodulator treatment in people with multiple sclerosis treated in reference centers. Cross-sectional study conducted with 188 people who used immunomodulators in three reference centers in Ceará from March to July 2012. Adherence was assessed using the Moriskscale and factors were assessed using a questionnaire addressing socioeconomic and personal characteristics, the disease, the use of immunomodulator and educational activities. The determination of the association was expressed in crude and adjusted odds ratio with a 95% confidence interval. Adherence rate was 46% and after the logistic regression model the adherence to immunomodulator treatment was positively associated with the following factors: age 18-38 years, time of diagnosis and treatment between 6 and 24 months, 0-3.5 score in the Expanded Disability Status Scale, perception of treatment benefits, intrinsic and extrinsic motivation, phone contact with the doctor and not missing the return visit. This study is important because it allowed to determine the association between factors and adherence to immunomodulator treatment in multiple sclerosis, contributing to prevention and control actions.

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Published

2017-01-01

Issue

Section

Articles

How to Cite

Factors associated with adherence to immunomodulator treatment in people with multiple sclerosis. (2017). Brazilian Journal of Pharmaceutical Sciences, 53(1), e16132-. https://doi.org/10.1590/s2175-97902017000116132